Thursday, June 27, 2013

Federal Circuit Begins its Campaign for Patent Clarity - Patent Law ...

By Dennis Crouch

Wyeth v. Abbot Labs (Fed. Cir. 2013)

In a unanimous opinion, the Federal Circuit has affirmed a summary judgment holding that Wyeth's patents are invalid as lacking enablement under 35 U.S.C. 112. Wyeth's patents cover the use of rapamycin antibiotic to treat and prevent restenosis following arterial balloon catheterization. See U.S. Patent Nos. 5,516,781 and 5,563,146. The claimed invention is simple and basically says, administer an "antirestenosis effective amount of rapamycin." Claim 1 of the '781 patent reads as follows:

1. A method of treating restenosis in a mammal resulting from said mammal undergoing a percutaneous transluminal coronary angioplasty procedure which comprises administering an antirestenosis effective amount of rapamycin to said mammal orally, parenterally, intravascularly, intranasally, intrabronchially, transdermally, rectally, or via a vascular stent impregnated with rapamycin.

One requirement of patent law is that the patent application (at the time of its filing) must sufficiently enable a person skilled in the relevant art to make and use the full scope of the claimed invention without undue experimentation. This "enablement requirement" is codified in Section 112(a) of the Patent Act (Formerly known as Section 112?1).

Here, it is the "full scope" requirement that kills the patent. In particular, Wyeth requested and received a broad construction of the claim term rapamycin to in a way that includes a large number of molecules that are structurally analogous to one another. However, the specification only discloses a single species along with a number of assays that could be useful to ascertain whether potential compounds exhibit the requisite effect.

In the appeal, the Federal Circuit aligned itself to the rule that broad claim scope requires broad disclosure. Here, the court noted that the rapamycin definition includes "tens of thousands" of candidate molecules and the specification "is silent about how to structurally modify sirolimus.

Undue experimentation: For its part, Wyeth argued that a lab tech with the usual skill and little creativity could systematically work through the various potential candidates to find which ones actually work. Citing to Johns Hopkins Univ. v. CellPro, Inc., 152 F.3d 1342, 1360?61 (Fed. Cir. 1998), Wyeth argued that a large pile of merely routine experimentation does rise to the level of impermissible undue experimentation.

The Federal Circuit disagreed ? finding that the trial-and-error process of tens-of-thousands of candidates moves the project well into the range of undue experimentation.

[T]here is no genuine dispute that it would be necessary to first synthesize and then screen each candidate compound using the assays disclosed in the specification to determine whether it has immunosuppressive and antirestenotic effects. There is no evidence in the record that any particular substitutions outside of the macrocyclic ring are preferable. Indeed, a Wyeth scientist confirmed the unpredictability of the art and the ensuing need to assay each candidate by testifying that, "until you test [compounds], you really can't tell whether they work or not [i.e., have antirestenotic effects]." J.A. 6929. In sum, there is no genuine dispute that practicing the full scope of the claims would require synthesizing and screening each of at least tens of thousands of compounds. . . .

Even putting the challenges of synthesis aside, one of ordinary skill would need to assay each of at least tens of thousands of candidates. Wyeth's expert conceded that it would take technicians weeks to complete each of these assays. The specification offers no guidance or predictions about particular substitutions that might preserve the immunosuppressive and antirestenotic effects observed in sirolimus. The resulting need to engage in a systematic screening process for each of the many rapamycin candidate compounds is excessive experimentation. We thus hold that there is no genuine dispute that practicing the full scope of the claims, measured at the filing date, required undue experimentation.

The take-away legal points here are (1) broad claims must do more to satisfy the enablement requirement than narrow claims; and (2) when excessive, routine non-creative efforts to recreate the invention can constitute undue experimentation.

The case is also interesting because it comes at a time where policymakers are looking to tighten the requirements of Section 112. As it did during the debate over the AIA, the Federal Circuit appears poised to make its mark on the current debate over patent scope and clarity.

Source: http://www.patentlyo.com/patent/2013/06/federal-circuit-begins-its-campaign-for-patent-clarity.html

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IG: IRS credit cards used for wine, pornography

WASHINGTON (AP) ? Poor oversight by the Internal Revenue Service allowed workers to use agency credit cards to buy wine for an expensive luncheon, dorky swag for managers' meetings and, for one employee, romance novels and diet pills, an agency watchdog said Tuesday.

Two IRS credit cards were used to buy online pornography, though the employees said the cards were stolen. One of the workers reported five agency credit cards lost or stolen.

IRS employees used agency credit cards to make more than 273,000 purchases totaling nearly $108 million in 2010 and 2011, according to the report by the Treasury inspector general for tax administration.

The vast majority of those purchases were legitimate, the report said. However, the report said the IRS has inadequate controls to prevent inappropriate purchases.

For example, investigators found that one IRS employee spent $2,655 on diet pills, romance novels, steaks, a smartphone and baby-related items, including bottles, games and clothes. The case was referred to the IG's office that investigates employee misconduct, the report said.

Among other "improper" purchases identified by the inspector general:

? $3,152 to rent a popcorn machine and to buy prizes for an employee event, including bandanas, stuffed animals, sunglasses and stovepipe hats.

? $418 for novelty decorations and swag at managers' meetings, including kazoos, bathtub toys and "Thomas the Tank Engine" wristbands.

? $119 for Nerf footballs that were never used and were found stored in a filing cabinet.

"Inadequate procedures to identify, report and address inappropriate use leaves the IRS purchase card program vulnerable to repeated violations of applicable laws and regulations," said J. Russell George, the Treasury inspector general for tax administration.

The report comes as the IRS faces intense scrutiny over agents targeting conservative groups for additional scrutiny when they applied for tax-exempt status. Documents released Monday show that liberal and progressive groups were singled out, too.

Also, the inspector general released a report earlier this month that detailed lavish spending at employee conferences. In all, the agency spent nearly $50 million on employee conferences from 2010 through 2012.

"Clearly, any inappropriate card use impacts our bottom line and is cause for concern," said acting IRS Commissioner Danny Werfel, who took over the agency last month. "Wasteful spending cannot be tolerated, and any employees found to be abusing the system will be held accountable. In fact, we are following up on several inappropriate incidents mentioned in the report, ranging from internal actions to criminal charges."

"That said, more than 99.75 percent of IRS purchases adhered to the rules," Werfel added. "The IRS has made important progress over the past two years in strengthening the controls in our purchase card program. We are committed to protecting taxpayer resources, and we will take quick action to implement all of TIGTA's recommendations."

The new report highlighted a 2010 conference in Washington for tax officials from other countries. At a luncheon, the IRS bought 28 bottles of wine ? for 41 guests, the report said. A dinner at the conference cost the agency $140 a person, four times the allowable government rate at the time.

In all, the agency spent more than $50,000 on meals, receptions and meetings at the five-day conference, the report said. Agency credit cards were used for about $12,500 of the purchases.

"It is important to note that the luncheon described in the report took place in 2010 for an international business meeting of tax officials from several of the world's largest countries. This meeting is an important forum for international leaders on major tax issues," Werfel said. "However, given the excessive purchases for the luncheon, I am directing the IRS business units to more closely review spending in advance for any similar events to ensure all spending is appropriate."

The IRS participates in the General Services Administration's SmartPay purchase card program. Under the program, agency employees can use purchase cards, which act like credit cards, to buy work-related items. The maximum amount for an individual purchase is $3,000.

More expensive items are subject to competitive pricing policies.

In 2010 and 2011, internal controls at the IRS found 327 cases in which employees divided their purchases to skirt the $3,000 limit. The inspector general's office found an additional 34 cases. In all, the purchases totaled $493,000, the report said.

The report said 94 employees were responsible for the purchases, including 22 workers who had done it more than once in a six-month period. However, the report said, none of the employees were disciplined.

As for the two IRS employees whose cards were used to buy pornography, the inspector general's report didn't determine who bought the material or whether their cards were actually stolen. One of the employees is no longer at the agency. The IG is continuing to investigate the other employee, the report said.

___

Follow Stephen Ohlemacher on Twitter: http://twitter.com/stephenatap

Source: http://news.yahoo.com/ig-irs-credit-cards-used-wine-pornography-190551115.html

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Obama Lays Out Broad Plan To Address Climate Change

The Capitol dome is seen behind the Capitol Power Plant, which provides power to buildings in the Capitol complex in Washington, D.C.

Carolyn Kaster/AP

The Capitol dome is seen behind the Capitol Power Plant, which provides power to buildings in the Capitol complex in Washington, D.C.

Carolyn Kaster/AP

Update at 2:38 p.m. ET. Obama Lays Out Plan:

In an address at Georgetown University in Washington, President Obama laid out a sweeping new plan to address climate change.

As expected, Obama said his plan seeks to cap the carbon emissions of power plants.

Obama also said the Keystone XL pipeline, which would carry oil from Canada to Texas, would only be approved by the State Department if it aligned with the "nation's interest."

That is if "this project does not significantly exacerbate the problem of carbon pollution," Obama said.

Now remember, the State Department already released a draft environmental assessment of the project that found the 1,700 mile pipeline will "not have a huge impact on climate."

Our Original Post Continues:

President Obama is expected to announce a sweeping plan to address climate change this afternoon.

Read the plan and a White House fact sheet.

The president has framed this issue as a moral responsibility, to leave the Earth in good shape for generations to come. But the nitty-gritty of any serious plan to address this problem is also a challenge, because it means gradually moving away from fossil fuels to renewable energy supplies ? and that means there will be economic winners and losers.

Winners include companies that produce clean energy ? wind, solar and geothermal energy. That energy will be more in demand, and the administration intends to expand access to public lands, where companies can build windmills and solar facilities.

Public health is also a winner, because the plan would pressure coal-fired power plants to reduce their emissions. Those plants not only produce carbon dioxide, but they are major sources of mercury, radioactive particles and chemicals that contribute to asthma.

Losers under this plan would eventually be coal mining companies and utilities that burn a lot of coal. That's because ? for the first time ? the government plans to limit how much carbon dioxide existing power plants can put into the air. It's a key element of the new plan, but it's also unclear just what form it will take. Those limits are supposed to be negotiated over the coming year, with input from industry as well as the states. The president's 21-page plan calls for them to be finalized in 2015, according to administration officials.

If those limits are aggressive, they could drive up electricity prices. But if the limits are too relaxed, they won't have much of an effect on emissions.

Overall, the president is striving to reach an emissions-reduction goal he laid out at the 2009 United Nations climate talks in Copenhagen: to reduce U.S. emissions by 17 percent, relative to our 2005 emissions, by the year 2020. The nation is not currently on track to meet the goal, despite some aggressive fuel-efficiency standards for new cars and a big expansion of renewable energy supplies during President Obama's first term. This new climate policy is intended to close the gap.

The plan also calls for the government to keep working internationally to reduce emissions, since climate change requires a global response. And even with a good international effort, some climate change is already inevitable. So the White House policy calls on efforts to adapt to a world with more extreme weather events.

For example, new standards for roads would assure that they are built high above flood levels. Farmers would be provided with ways to adapt to more drought conditions. And local governments would get assistance to help them plan for extreme weather.

All of these proposals can be enacted without action on Capitol Hill. That's deliberate. Many Republicans in congress reject the judgment of the National Academy of Sciences and other authorities who say climate change is a real concern.

Take me back to the top of this post.

Source: http://www.npr.org/blogs/thetwo-way/2013/06/25/195466923/obama-to-lay-out-broad-plan-to-address-climate-change?ft=1&f=1007

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Tuesday, June 25, 2013

Imgur's Android app distracts you with cute kittens on the go

DNP Imgur Android app

Imgur, a reservoir of viral photos, adorable kittens and vapid memes, is going mobile: it's releasing an official Android app today. Technically, the app has been floating around Google Play since April, albeit in beta form. The final build allows users to view and comment on photos, as well as to upload their own -- basically everything the service's full website offers. Read on for the company's full press release, or check out the source link below to fuel your mindless addiction.

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Source: Google Play

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US tones down demands that Russia expel NSA leaker (The Arizona Republic)

Share With Friends: Share on FacebookTweet ThisPost to Google-BuzzSend on GmailPost to Linked-InSubscribe to This Feed | Rss To Twitter | Politics - Top Stories News, RSS Feeds and Widgets via Feedzilla.

Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/315197156?client_source=feed&format=rss

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Deadly piglet virus spreads to nearly 200 U.S. farm sites

By P.J. Huffstutter

CHICAGO (Reuters) - A swine virus deadly to young pigs, and never before seen in North America, has spiked to 199 sites in 13 states - nearly double the number of farms and other locations from earlier this month.

Iowa, the largest U.S. hog producer, has the most sites testing positive for Porcine Epidemic Diarrhea Virus: 102 sites, as of June 10. The state raises on average 30 million hogs each year, according to the Iowa Pork Producers Association.

PEDV, most often fatal to very young pigs, causes diarrhea, vomiting and dehydration. It also sickens older hogs, though their survival rate tends to be high.

The total number of pig deaths from the outbreak since the first cases were confirmed May 17 is not known.

Researchers at veterinarian diagnostic labs, who are testing samples as part of a broad investigation into the outbreak, have seen a substantial increase in positive cases since early June, when data on the PEDV outbreak showed it at some 103 sites nationwide.

The data was compiled and released last week by Iowa State University, University of Minnesota, Kansas State University and South Dakota State University.

The virus does not pose a health risk to humans or other animals and the meat from PEDV-infected pigs is safe for people to eat, according to federal officials and livestock economists.

But the virus, which is spreading rapidly across the United States, is proving harder to control than previously believed. In addition to Iowa, Oklahoma has 38 positive sites, Minnesota has 19 and Indiana has 10, according to the data.

PEDV has also been diagnosed in Arkansas, Colorado, Kansas, Illinois, Michigan, Minnesota, Missouri, Ohio, Pennsylvania and South Dakota.

Swine veterinarians, investigators with the U.S. Agriculture Department and others are trying to determine how the virus is spreading from farm to farm and state to state. Currently the focus is on the nation's livestock transportation system.

PEDV is spread most commonly by pigs ingesting contaminated feces. Investigators are studying physical transmission, such as truck trailers marred with contaminated feces, or a person wearing dirty boots or with dirty nails.

While the virus has not tended to kill older pigs, mortality among very young pigs infected in U.S. farms is commonly 50 percent, and can be as high at 100 percent, say veterinarians and scientists who are studying the outbreak.

The strain of the PEDV virus that is making its way across the nation's hog farms and slaughterhouses is 99.4 percent similar in genetic structure to the PEDV that hit China's herds last year, according to the U.S. researchers.

After PEDV was first diagnosed in China in 2010, it overran southern China and killed more than 1 million piglets, according to the Centers for Disease Control and Prevention's Emerging Infectious Diseases Journal.

No direct connection has been found between the U.S. outbreak and previously identified outbreaks in Asia and Europe, say scientists and researchers.

(Reporting by P.J. Huffstutter. Additional reporter by Theopolis Waters.; Editing by Bob Burgdorfer)

Source: http://news.yahoo.com/deadly-piglet-virus-spreads-nearly-200-u-farm-215056693.html

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Leap Motion Controller Hands-On: The Future Is Magic (Now With Apps!)

Leap Motion Controller Hands-On: The Future Is Magic (Now With Apps!)

Greasy fingers are the bane of touchscreens, obscuring the display behind snail trails of oil and streaks of grime. Forget that mess. Leap Motion has promised hands-free PC navigation for months now, and after some hands-on time we can confirm that the future is here, and it's amazing.

As a brief refresher, the Leap Motion Controller tracks your hand and finger movements in three-dimensional space, allowing users to recreate multitouch input without actually touching anything. You just wave your hands and wiggle your fingers in the air over it and boom, your computer responds.

Leap Motion Controller Hands-On: The Future Is Magic (Now With Apps!)

It will be available for Windows 7 and 8, as well as Mac OS X 10.6 and above, when the $80 device hits store shelves on July 29th (though if you pre-ordered, it's out on the 22nd). It won't be available for mobile to start but the company is looking into potentially integrating the technology with a number of OEMs.

With a few waves of your hands, both native applications?from web browsers to Google Earth?and system navigations respond instantly to your commands. The company is also developing Airspace, an online hub for LeapMotion-enabled applications.

Leap Motion Controller Hands-On: The Future Is Magic (Now With Apps!)

"Everything you can do with a touch-based system, like Windows 8, can now be accomplished with LeapMotion technology. We want our users to have a magical experience, with easy and natural movements in the air leading to amazing interactions. This is the foundation for our approach to existing systems," David Holz, co-founder and CTO of LeapMotion, said in a press statement. "But this is only the beginning. The potential for our 3D interaction technology is really unleashed by applications built specifically for LeapMotion, helping drive the future of computing."

Leap Motion Controller Hands-On: The Future Is Magic (Now With Apps!)

I had the opportunity to try out the Leap Motion last week, and great googly moogly this thing is amazeballs. It tracks both hands?their position, angle, rotation, orientation, everything?in real time, as well as the positions and movements of all three joints in all ten fingers. The controller registers everything within a roughly foot-tall, 18-inch-wide dome-shaped area surrounding the controller and is wildly accurate, picking up even miniscule finger twitches. During the demo, used Google Earth to fly around Lower Manhattan like I was the kid from Flight of the Navigator, I played a 3D variation of Brick Breaker using my index fingers as paddles to punch, poke, and prod the ball around the arena, and I navigated around both OS X and Windows 8 systems by swiping my hands through the air.

It was strange, initially, getting used to moving the cursor without grabbing a mouse or tapping the screen but it only takes a second to get the hang of the process. The controller can also be set to use either basic controls (taps, swipes, and other common input commands) or more advanced gestures, which helps ease you into it as well.

Granted, I played with this device for all of 15 minutes in a controlled environment (LeapMotion's SF office) but that was a glorious quarter hour; I felt like Tony Stark using the Jarvis UI. July 29th can't come soon enough.

Source: http://gizmodo.com/leap-motion-controller-hands-on-the-future-is-magic-530869578

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Monday, June 24, 2013

Source: Snapchat Snaps Up $80M From IVP At An $800M Valuation

Screen Shot 2013-06-22 at 11.42.55 PMIt's the second day of summer, and Snapchat has raised an $80 million Series B round at an $800 million pre-money valuation, according to a source. The phat Series B round was led by Institutional Venture Partners,?according to multiple sources, after being sought after by many other top-tier Valley VCs.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/Bu5jBlKBuVY/

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Gunmen kill 11 foreign tourists in Pakistan

ISLAMABAD (AP) ? Gunmen killed 11 foreign tourists before dawn Sunday as they were visiting one of the world's highest mountains in a remote area of northern Pakistan, police said.

The tourists from Russia, China and the Ukraine were shot dead at the base camp of Nanga Parbat, the ninth highest mountain in the world, said local police chief Barkat Ali. It's unclear if they were planning to climb the mountain or were just visiting the base camp, which is located in the Gilgit-Baltistan region of Pakistan.

The police chief learned about the attack when the tourists' local guide called the police station around 1 a.m. local time on Sunday, said Ali.

No one has claimed responsibility for the attack.

Pakistan is home to several insurgencies and internal conflicts but Gilgit-Baltistan is generally a peaceful area, although it has experienced some sectarian violence between Sunni and Shiite Muslims in recent years. The area is a popular destination for tourists because it includes a large number of very tall mountains in the Himalayan and Karakoram ranges, including K2, the second highest mountain in the world.

Source: http://news.yahoo.com/gunmen-kill-11-foreign-tourists-pakistan-052935406.html

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PFT: Jaguars ink No. 2 overall pick Joeckel

LeBronGetty Images

The Dolphins gritted their teeth and celebrated the success of the local NBA franchise that makes the local NFL franchise even less relevant locally.? And nationally.

There will be more cops at Bills games this year.? (Fans would prefer more points.)

The University of Florida connection isn?t working out for the Patriots.

Get to know Jets S Josh Bush.

Browns S T.J. Ward likes Ray Horton?s aggressive style; ?It?s an attack style, all downhill. We?re really getting after the guys. That?s what I?m most excited about,? Ward said, proving that the point can be conveyed without using terms like ?kill? or ?hurt? or ?inflict mild bruising.?

The Ravens last 2013 draft pick, CB Marc Anthony, hopes to win a job with ?physicality and versatility.?

Former Steelers K Jeff Reed did a little bragging recently about his ownership of two Super Bowl rings.

Bengals single-game tickets go on sale June 29; pre-registration was required for visits from the Steelers and the Packers.

Texans WR Andre Johnson and S Ed Reed made it to the teens on NFL Network?s Top 100 countdown.

Colts DL Ricky Jean Francois still gets advice from Donald Heaven, who played OT at Florida State when Jean Francois arrived in 2002.

Titans G Chance Warmack is trying to stay positive as he makes the transition from college to the NFL.

The enhancements to the Jaguars stadium will start after the 2013 season and are expected to be ready by the start of the 2014 season.

Chargers FB Le?Ron McClain is holding a free football camp for kids in Alabama on Saturday.

Ditto for Chiefs RB Jamaal Charles, who started his fourth annual free camp for 175 kids on Friday in Texas.

Whatever Broncos WR Wes Welker got paid this week to talk repeatedly about his hair plugs, it wasn?t nearly enough.

When news broke that actor James Gandolfini has passed, some fans thought Raiders assistant Tony Sparano had died.

Cowboys QB Tony Romo didn?t earn a spot on NFLN?s Top 100 list, after coming in at No. 91 in 2012 and No. 72 in 2011.

The Associated Press style book would seem to suggest that any publication adhering to it should not use the term Redskins.

A New Jersey accountant who allegedly scammed the state out of nearly $700,000 in false unemployment claims used the money to buy, among other things, Giants season tickets.

Kyle Shurmur, the son of Eagles offensive coordinator Pat Shurmur, is 6-4 and slated to play quarterback for La Salle High School.

The Packers have reduced from nine night training-camp practices in 2012 to zero in 2013.

Retired Bears LB Brian Urlacher is playing a lot of golf; ?The first thing on my mind when I wake up isn?t working out anymore,? Urlacher said.? ?So that?s a good thing.?

Vikings CB Xavier Rhodes arrived at Florida State as a receiver, and when he was moved to defense he initially wanted to transfer.

LB Jon Morgan is trying to win a spot on the Lions roster as an undrafted free agent.

Saints WE Marques Colston is hosting a receivers camp on Saturday for kids 10 to 18 years old.

50 sacks may be a bit unrealistic, but Panthers LB Greg Hardy could be in for a big year.

A 150-year-old church in Atlanta wants $24.5 million to move from the footprint of the Change Purse; the city has offered $15.5 million.

The Buccaneers? ?Rookie Club? spent time this week with local kids in Tampa.

So how can players like 49ers WR Michael Crabtree recover so quickly from a torn Achilles tendon?

Cardinals running backs coach Stump Mitchell is helping rookie RB Stepfan Taylor catch up after missing the offseason program due to the ridiculous, outdated, and unfair rule that prevents first-year players from working until the students at the college the players no longer attend have taken their final exams.

Seahawks DE Michael Bennett told the Real Rob Report that he?s never seen a pace like the one at Seahawks practices.

35 first-year Rams stuck around for ?Rookie Week,? an up-close introduction to St. Louis.? (Which for most of them will be completely irrelevant by September.)

Source: http://profootballtalk.nbcsports.com/2013/06/22/jaguars-agree-to-terms-with-no-2-overall-pick-luke-joeckel/related/

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Thursday, June 20, 2013

Qualcomm Snapdragon 800 MDP benchmarks: prepare for ludicrous speed

Qualcomm Snapdragon 800 MDP benchmarks prepare for ludicrous speed

Today we had a chance to play with Qualcomm's latest MDP devices (tablet and phone) which pack the company's mighty Snapdragon 800 SoC (MSM8974). The tablet is slightly larger than last year's MDP and features a 11.6-inch 1920 x 1080 pixel display, 2GB of LPDDR3 RAM, 32GB of built-in flash storage (with microSD expansion) and a 12 megapixel AF rear camera with flash (2MP in front). All of this is crammed into a slim (0.46 inches / 11.7mm) chassis that's powered by a 3400mAh Li-ion battery and incorporates a bevvy of radios (LTE, WiFi ac, Bluetooth 4 LE, GPS, NFC) and sensors (including pressure and humidity).

The phone shares most of the tablet's specs but swaps the screen for a 4.3-inch panel (1280 x 720 pixels) and the battery for a smaller (1500mAh) pack. We put the Snapdragon 800-equipped MDPs through their paces by running our usual suite of benchmarks (plus a few more). The results? Prepare for ludicrous speed. More after the break.

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Wednesday, June 19, 2013

AstraZeneca, Bristol diabetes drug fails to show heart benefit

LONDON (Reuters) - AstraZeneca and Bristol-Myers Squibb's diabetes drug Onglyza failed to reduce heart risks in a large clinical study.

The companies, which jointly sell several diabetes drugs, said on Wednesday the so-called SAVOR trial showed that patients on Onglyza had no fewer adverse cardiovascular events, such as heart attacks and strokes, than those on placebo.

Doctors and investors had been awaiting results of the SAVOR trial with keen interest and a positive result could have encouraged increased use of the drug.

In the event, the study found Onglyza was no worse than placebo or standard care in terms of cardiovascular outcomes, but it failed to meet the goal of demonstrating superiority.

(Reporting by Ben Hirschler, Editing by Rosalba O'Brien)

Source: http://news.yahoo.com/astrazeneca-bristol-diabetes-drug-fails-show-heart-benefit-062113731.html

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Religions seen slow to go green; Pope has chance to inspire

By Environment Correspondent Alister Doyle

OSLO (Reuters) - Few religious communities have gone as far in fighting climate change as a church in Queensland, Australia, which has 24 solar panels bolted to the roof in the shape of a Christian cross.

"It's very effective. It's inspired some members of our congregation to install panels on their homes," Reverend David Lowry said of the "solar cross" mounted in 2009 on the Caloundra Uniting Church, which groups three Protestant denominations.

Many religions have been wary of moving to install renewable energy sources on their places of worship, from cathedrals to mosques - or of taking a strong stand on climate change in general - despite teachings that people should be custodians of nature.

But slowly, that may be changing, thanks to new religious leaders including Pope Francis, the head of the Roman Catholic Church.

Francis's stress on environmental protection since he was elected in March and his choice of the name of a 13th century nature lover - Saint Francis of Assisi - may make a difference for all religions trying to work out how to safeguard the planet from threats including climate change.

Under his predecessor, Pope Benedict XVI, the Vatican took green steps such as installing solar panels on the roof of the Papal Audience Hall in 2008. It says it wants to cut greenhouse gas emissions, but has no formal target.

"Religious environmentalism is slowly increasing," said John Grim, a coordinator of the forum on religion and ecology at Yale University in the United States. "It's very uneven. Religions tend to be very conservative in their practice and doctrine."

SAFEGUARD THE EARTH

Grim said the pope's influence was significant since few other religions recognize a single earthly leader - and there are 1.2 billion Catholics, amounting to a sixth of humanity, according to the Vatican.

In his inaugural homily, Pope Francis stressed that people should safeguard the Earth.

"Let us be 'protectors' of creation, protectors of God's plan inscribed in nature, protectors of one another and of the environment. Let us not allow omens of destruction and death to accompany the advance of this world!" he said.

In a 2010 book "On Heaven and Earth", when he was archbishop of Buenos Aires, he said mankind sometimes lost respect for nature. "Then ecological problems arise, like global warming."

Some religions have been reluctant to be associated with climate change policies because of divisions among believers. A 2012 Pew Research Center poll showed that only 42 percent of Americans agree global warming is mainly man-made, a view overwhelmingly held by climate scientists, for example.

The Church of England says it aims to cut its carbon emissions by 42 percent by 2020 and 80 percent by 2050 across widely varying energy use in 16,000 buildings, but it is an exception.

"Some churches are used all week and others used very occasionally, with only one light bulb," said David Shreeve, environmental advisor to the Archbishops' Council. He said other religions were now asking for advice on emissions cuts. Irrespective of climate change, big savings can be made by plugging draughts and improving heating and lighting.

Some believers object that solar panels can damage or disfigure fragile historic buildings. Some cathedrals, like the Catholic Saint Stephens in Vienna, have elaborate patterns on the roof.

Bradford Cathedral, where the oldest parts of the Nave date from 1458, installed solar panels in 2011 and said it was the first cathedral in England - and perhaps in the world - to generate its own power.

Among other examples, a planned mosque in Bursa, west Turkey, aims to use solar panels and install a vertical axis wind turbine - without big revolving blades - on a minaret.

"Mosques ... can be covered with photovoltaic panels," the mosque's architect ?elik Erengezgin said.

Green initiatives by religious leaders and groups are not new.

The Jewish Temple Emanuel in Lowell, Mass., installed solar panels in 1978 in what is believed to be the first such system on a religious building in North America, the Lowell Green Building Commission says.

And Greek Orthodox Ecumenical Patriarch Bartholomew, spiritual leader of the world's Orthodox Christians, has long been called the "Green Patriarch" for seeking to protect the environment, from organizing conferences about fresh water to writing an encyclical in 2012 urging repentance for "our sinfulness in destroying the world".

Saint Francis has long been a green inspiration.

In what are known as the Assisi Declarations from 1986, Buddhist, Christian, Hindu, Jewish and Islamic leaders called for people to live in harmony with nature. Baha'i, Jainism and Sikhism later added their own declarations.

HOLY SEE

In the United States, many evangelical Christians stress a broad need for "stewardship of creation", rather than man-made climate change, as a spur to action.

Many evangelical Christians are Republicans who are more likely than Democrats to doubt that climate change is mostly caused by human activity, such as burning fossil fuels.

"Americans allow their politics to inform their faith," said Katharine Hayhoe, an evangelical Christian and climate scientist at Texas Tech University.

In Australia, Lowry said the solar panels were saving money and cutting greenhouse gas emissions for the Uniting Church, which brings together Methodists, Congregationalists and Presbyterians.

"The solar cross ... doesn't bring hordes of people into the church," he said. "But it helps people understand that God is a presence in the world in which we live."

The Vatican has an observer seat at U.N. talks among 200 nations who have agreed to work out, by the end of 2015, a climate deal to avert more floods, droughts and rising sea levels.

Pope Francis himself has focused on environmental protection without yet spelling out clear solutions.

Raising awareness of the environment could be a step to modernize the Church, besieged by scandal for covering up sexual abuse of children by priests and whose strict moral traditions are often at odds with a increasingly secular society.

"With Pope Francis there is new hope," said Reverend Henrik Grape of the Church of Sweden, who is also a member of the World Council of Churches' climate change group.

(Additional reporting by Tom Heneghan in Paris; Editing by Sonya Hepinstall)

Source: http://news.yahoo.com/religions-seen-slow-green-pope-chance-inspire-140434701.html

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Three ways to bring added entertainment to your outdoor experiences

There?s a reason it?s called the ?great? outdoors. Nothing can quite compare with the beauty and majesty of wild places. When summer rolls around, the urge to explore grows for many people, inspiring millions of travelers to camp, hike and tour the country?s natural wonders. Modern outdoor enthusiasts have discovered that technology makes it even more fun to spend time in off-the-beaten-track locations.

The days of canvas tents and campsite boredom are long gone, thanks to tech innovations that are changing the face of outdoor experiences. For example, have you ever wanted to watch a little TV while out on the boat or at the campsite? Maybe kick back with some s?mores and a movie? Today, you truly can do it ? and you?ll get much more than you ever expected.

There are a few ways to bring your favorite programs and movies with you into the outdoors, covering a range in terms of both what you can do with them and where you can use them. These are the key choices to consider before you pack up for your next outdoor adventure:

* Good: A TV or computer with a DVD player is one way to get the movies you want, as well as some TV shows (provided they?re out on DVD). If you don?t mind a limited selection and have the storage capacity to bring along all the titles you or the kids might want, it?s a solid, basic option.

* Better: Being able to pick up free local channels gives you access to the network programs such as The Big Bang Theory, NCIS and The Voice, plus local news that will keep you up to date on regional happenings and the all-important weather forecast. But you?ll need the right antenna. The RAYZAR Amped HD antenna from Winegard Co. has the strength to pull signals from 50 miles away. Even if you?re deep in the wilderness, you can still get news, entertainment and a great picture. It?s easy to set up, portable and is designed for use indoors only ? perfect for RVs, boats and campers.

* Best: For the ultimate range in entertainment, a satellite TV antenna is the optimal choice. The CarryOut Anser, also made by Winegard, works with both DISH and DirecTV subscriptions, giving you access to a vast array of programming such as Duck Dynasty, Sports Center and more. With this system you can either use your satellite receiver from home or get DISH pay as you go programming and pay for only 30 days of programming at a time with no contracts or subscriptions. The portable antenna sets up outdoors quickly and can be used on multiple TVs at once, so everyone can enjoy different shows and movies at the same time.

For the ultimate in outdoor fun, whether you?re camping, traveling, boating or tailgating, don?t count technology out of the equation. With the convenience and fun that these outdoor TV-watching options can offer, they might just be the must-haves on your packing list for years to come. For more information, go to www.winegard.com.

Source: http://www.lifeandleisurenj.com/technology/three-ways-to-bring-added-entertainment-to-your-outdoor-experiences.html

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A Newbies Help Guide To Bass Sport fishing | nsnqfitness.com ...

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Source: http://fatranao.blogspot.com/2013/06/a-newbies-help-guide-to-bass-sport.html

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Tuesday, June 18, 2013

Navarrette: 'Mariachi singer' more American than critics (CNN)

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Obama, Putin face tough talks on Syria

By Guy Faulconbridge

LOUGH ERNE, Northern Ireland (Reuters) - President Barack Obama will seek the help on Monday of Russia's Vladimir Putin, Syria's most powerful ally, to bring Bashar al-Assad to the negotiating table and end a two-year civil war.

At their first private face-to-face meeting in a year, Obama will try to find common ground with Putin on the sidelines of a G8 summit in Northern Ireland after angering the Kremlin by authorising U.S. military support for the Syrian president's opponents.

During talks with British Prime Minister David Cameron in London on the eve of the summit, Putin renewed his criticism of the West's position in startling tones, describing Assad's foes as cannibals.

"I think you will not deny that one does not really need to support the people who not only kill their enemies, but open up their bodies, eat their intestines, in front of the public and cameras," Putin said at a joint news conference with Cameron.

"Are these the people you want to support? Is it them who you want to supply with weapons?"

Cameron conceded London and Moscow remained far apart.

Russia does not buy the West's assertion that Assad's forces have used chemical weapons and crossed a red line in doing so, saying U.S. military support for Syrian rebels would only escalate violence.

Washington said on Saturday it would keep F-16 fighters and Patriot missiles in Jordan at Amman's request, prompting Moscow to bristle at the possibility they could be used to enforce a no-fly zone inside Syria.

Putin's rhetoric has become increasingly anti-Western since he regained the presidency last year but he appeared upbeat in London, stressing several areas of cooperation between Russian and Britain.

At the Lough Erne golf resort in Northern Ireland, Cameron will bring together leaders of the United States, Japan, Canada, Russia, Germany, France and Italy - representing just over half of the $71.7 trillion global economy.

Syria will inevitably dominate the Monday-Tuesday talks but persistent worries about the global economy will also be central to the discussions.

MARKET TURMOIL TO FOCUS MINDS

Japanese Prime Minister Shinzo Abe, German Chancellor Angela Merkel and other leaders will likely discuss the role of central banks and monetary policy.

They are likely to say they are not content with progress so far in fixing their economies in the wake of the global financial crisis, according to a draft communique seen by Reuters.

Japan's Abe will use the opportunity to explain his cocktail of fiscal and monetary stimulus known as 'Abenomics' to the leaders as investors try to absorb the implications of a signal by the U.S. Federal Reserve that it may start to slow its money-printing.

Fed chairman Ben Bernanke will not attend. He and his colleagues hold a two-day policy meeting on Tuesday and Wednesday.

Bond yields have climbed and share prices have sagged globally since Bernanke shocked investors on May 22 by saying the bank might ?take a step down' in the pace of bond purchases - a blow to a global economy still growing well below trend due to the after effects of the great financial crisis.

"Japan's decisive moves to reflate its economy will support growth in the near term, but it will need to manage the twin challenge of providing near-term stimulus and achieving longer-term sustainability," the draft communique said, although the version circulated by Britain and seen by Reuters was put together before the recent market turmoil.

The leaders of the European Union and United States are likely to announce the start of formal negotiations on a free trade deal that could be worth more than $100 billion a year to each economy.

EU and U.S. negotiators aim to finish their work by the end of next year.

TREASURE ISLAND TAX

Cameron has made tackling tax avoidance - which campaigners say costs about $3 trillion a year - one of the key parts of the formal agenda at the summit.

He has turned up the pressure to clamp down on secretive money flows by pressing Britain's overseas tax havens into a transparency deal and announcing new disclosure rules for British firms.

"It is important we are getting our house in order," Cameron said on Saturday after representatives of overseas tax havens linked to Britain agreed to sign up to an international transparency protocol.

Aid campaigners said Britain's action will count for little if the rest of the G8 does not follow suit.

G8 leaders will probably shy away from adopting a measure aimed at curbing tax avoidance by highlighting when companies channel profits into tax havens, and will include a watered-down alternative, according to the draft communique.

Tackling corporate tax avoidance has become a political goal internationally following public anger about revelations over the past year that companies like Apple and Google had used structures U.S. and European politicians said were contrived to minimise the amount of taxes paid.

But the draft summit text suggested there will be no agreement on a rule that would force companies to publish their profits, revenues and tax payments on a country-by-country basis.

Global tax evasion could be costing more than $3 trillion a year, according to researchers from Tax Justice Network while as much as $32 trillion could be hidden by individuals in tax havens.

(Writing by Maria Golovnina, editing by Mike Peacock)

Source: http://news.yahoo.com/obama-putin-face-tough-talks-syria-g8-summit-230407848.html

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Monday, June 17, 2013

In the Ivory Tower, Men Only

Young academic woman. Before even applying for the first tenure-track job, many women with children have already decided to drop out of the race

Photo by Cristi M/iStockphoto/Thinkstock

In 2000, I greeted the first entering graduate-student class at Berkeley where the women outnumbered the men. I was the first female dean of the graduate division. As a ?70s feminist I cautiously thought, ?Is the revolution over? Have we won?? Hardly. That afternoon I looked around the room at my first dean?s meeting and all I saw were grey haired men. The next week at the first general faculty meeting of the semester I noted that women were still only about a quarter of the faculty, and most were junior.

Our Berkeley research team has spent more than a decade studying why so many women begin the climb but do not make it to the top of the Ivory Tower: the tenured faculty, full professors, deans, and presidents. The answer turns out to be what you?d expect: Babies matter. Women pay a ?baby penalty? over the course of a career in academia?from the tentative graduate school years through the pressure cooker of tenure, the long midcareer march, and finally retirement. But babies matter in different ways at different times. A new book I co-wrote with the team at Berkeley, Do Babies Matter? ?Gender and Family in the Ivory Tower, draws on several surveys that have tracked tens of thousands of graduate students over their careers, as well as original research.

The most important finding is that family formation negatively affects women?s, but not men?s, academic careers. For men, having children is a career advantage; for women, it is a career killer. And women who do advance through the faculty ranks do so at a high price. They are far less likely to be married with children. We see more women in visible positions like presidents of Ivy League colleges, but we also see many more women who are married with children working in the growing base of part-time and adjunct faculty, the ?second tier,? which is now the fastest growing sector of academia. Unfortunately, more women Ph.Ds. has meant more cheap labor. And this cheap labor threatens to displace the venerable tenure track system.

The early years are the most decisive in determining who wins and who loses. Female graduate students and postdoctoral fellows who have babies while students or fellows are more than twice as likely as new fathers or than childless women to turn away from an academic research career. They receive little or no childbirth support from the university and often a great deal of discouragement from their mentors. As one Berkeley graduate student who participated in our study put it, ?There is a pervasive attitude that the female graduate student in question must now prove to the faculty that she is capable of completing her degree, even when prior to the pregnancy there were absolutely no doubts about her capabilities and ambition.? And consider the postdoctoral particle physicist who brought a lawsuit that was settled. She was effectively blacklisted by her adviser when she had a baby. When she was pregnant, her adviser said he would refuse to write her a letter of recommendation unless she returned from her pregnancy leave soon after giving birth.

Before even applying for the first tenure-track job, many women with children have already decided to drop out of the race. They have perceived a tenure-track job as being incompatible with having children. In our study of University of California doctoral student, 70 percent of women and more than one-half of the men considered faculty careers at research universities not friendly to family life. Others are married to other Ph.D.s; the ?two body? problem. In those cases, one body must defer to the other?s career and that body is far more likely to be the woman?s. Or their husband?s career, not in academia, limits their choices. As one biology graduate student in our study said, ?My husband has a job he loves, but it will require that we don?t move: This limits my postdoc and career options significantly. I think the chances of staying in the same city throughout the career and finding a tenure track position are almost nonexistent. However, I am not sure I care any more.??

Then there is the job interview. One job candidate we interviewed said ? I also had the experience of being in an interview, mentioning my child, and seeing the SC?s [search committee head?s] face fall, and that was the end of the job. Although there could have been a million reasons, there is no doubt that having a child did not help my candidacy in that case.? Mothers are more likely to join the ranks of the second tier, or to drop out of academia

There is some good news for women. The second tier is not a complete career graveyard. We have found that a good proportion of those toiling as adjuncts and part-time lecturers do eventually get tenure track jobs. On the other hand, single, childless women get those first jobs at the higher rates than wives, mothers or single men?almost at the same rate as married fathers.

The pressure cooker years as an assistant professor leading up to tenure usually number four to seven years. At the end of this trial, the university decides ?up or out??tenure for life or dismissal. It is well established that women are less likely to be awarded tenure than men. There is a baby penalty, especially strong in the sciences?but women without children also receive tenure at a lower rate than men. There are other factors than children that cause women to fail at this critical juncture. The women who do make it often do so alone. Women professors have higher divorce rates, lower marriage rates, and fewer children than male professors. Among tenured faculty, 70 percent of men are married with children compared with 44 percent of women.

Source: http://www.slate.com/articles/double_x/doublex/2013/06/female_academics_pay_a_heavy_baby_penalty.html

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Bear with head stuck in jar is rescued in Pa.

JAMISON CITY, Pa. (AP) ? Four central Pennsylvania residents said they used only a rope and a flashlight during a wild chase to rescue a young bear whose head had been stuck in a plastic jar for at least 11 days.

The frightened but powerful bruin fell into a swimming pool at least twice during the ordeal, according to a report Saturday in the Press Enterprise of Bloomsburg (http://bit.ly/166z97k ). But the group eventually yanked off the jar and set the animal free.

"I thought, 'No one is going to believe us,'" said Morgan Laskowski, 22, the bartender at the Jamison City Hotel and a member of the impromptu bear-wrangling team.

Area residents first spotted the 100-pound bruin with its head in a red jar on June 3, but it eluded game wardens. The animal was attracted to the container because it appeared to have once contained cooking oil.

"He put his head in, and had a problem," said Mike Jurbala, 68, another rescuer. "He'd have died in a couple more days."

Jurbala saw the bear Thursday night as he was leaving the bar at the Jamison City Hotel. He called Jeff Hubler, a local employee of the state Game Commission who had been among those trying to capture it for days with a lasso.

The two teamed up with Laskowski and her mother, bar owner Jody Boyle, to follow the bear through the darkness.

"You knew where he was because you could hear him banging into things," Jurbala said.

They cornered the bear in a resident's backyard, where it ended up falling into a pool a couple of times. Eventually, they wrangled the animal into a position where Hubler could pull off the jar.

"You'd think the bear would be weak, because it hadn't eaten or drunk for a week, but it was strong," Boyle said.

Hubler said people should keep lids on food jars that they throw away.

___

Information from: Press Enterprise, http://www.pressenterpriseonline.com

Source: http://news.yahoo.com/bear-head-stuck-jar-rescued-pa-184741213.html

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Iran's president-elect says economy will take time

A supporter of Iranian presidential candidate Hasan Rowhani holds up his poster while celebrating Rowhani's victory, in Tehran, Iran, Saturday, June 15, 2013. Wild celebrations broke out on Tehran streets that were battlefields four years ago as reformist-backed Rowhani capped a stunning surge to claim Iran's presidency on Saturday, throwing open the political order after relentless crackdowns by hard-liners to consolidate and safeguard their grip on power. (AP Photo/Ebrahim Noroozi)

A supporter of Iranian presidential candidate Hasan Rowhani holds up his poster while celebrating Rowhani's victory, in Tehran, Iran, Saturday, June 15, 2013. Wild celebrations broke out on Tehran streets that were battlefields four years ago as reformist-backed Rowhani capped a stunning surge to claim Iran's presidency on Saturday, throwing open the political order after relentless crackdowns by hard-liners to consolidate and safeguard their grip on power. (AP Photo/Ebrahim Noroozi)

A supporter of Iranian presidential candidate Hasan Rowhani holds up a poster of Green Movement leader Mir Hossein Mousavi, who was a candidate in 2009 and is currently under house arrest, while celebrating Rowhani's victory, in Tehran, Iran, Saturday, June 15, 2013. Wild celebrations broke out on Tehran streets that were battlefields four years ago as reformist-backed Rowhani capped a stunning surge to claim Iran's presidency on Saturday, throwing open the political order after relentless crackdowns by hard-liners to consolidate and safeguard their grip on power. (AP Photo/Ebrahim Noroozi)

TEHRAN, Iran (AP) ? Iran's newly elected reformist-backed president said Sunday that the country's dire economic problems cannot be solved "overnight," as he took his first steps in consulting with members of the clerically dominated establishment on his new policies.

Hasan Rowhani's surprise victory in Friday's elections puts him in charge of an executive branch that traditionally has taken the lead in handling the economy, but nuclear efforts, defense and foreign affairs remain primarily in the hands of the ruling clerics and their powerful protectors, the Revolutionary Guard.

This creates a challenge for Rowhani, as Iran suffers from more than 30 percent inflation as well as 14 percent unemployment rates linked to Western sanctions for Tehran's suspect nuclear program. Rowhani has called for reaching out to the international community but has little authority over the nuclear activities tied to sanctions.

The semi-official ISNA agency said Rowhani discussed inflation and unemployment as well as possible members of his cabinet with Ali Larijani, speaker for Iran's conservative dominated parliament.

"Today, we took the first step for cooperation between two branches of power," Rowhani was quoted as saying. Rowhani will take office in August and needs parliament to approve his proposed nominees for 18 ministries.

Meanwhile, the Revolutionary Guard declared its willingness to cooperate with the president. "We announce our comprehensive readiness for interaction and cooperation with the next administration in the framework of legal duties and assignments," the Guard said on its webpage.

The outward displays of cooperation by Iran's establishment reflect its desire to close the political rift caused by unrest over disputed election results in 2009, and signal to world leaders that the ruling clerics are not publicly standing against Rowhani's call for outreach and dialogue with the international community.

Iran's stock exchange meanwhile climbed for the second continuous day. The rise came after a night of a celebration in Tehran, as the announcement of Rowhani's victory sent tens of thousands of jubilant supporters into the streets. Cars honked and blared music ranging from patriotic songs to the Lambada.

Riot police, who were frequently deployed on Tehran streets in the run-up to Friday's vote, were conspicuous in their absence. State TV showed footage of the celebrations and rebroadcast a speech he made after his victory was announced Saturday, asserting Iran's readiness to improve its ties with the world.

The website of the Tehran Stock Exchange said the market jumped 1,194 points by its closure at noon on Sunday, reaching 47,460 from its Saturday close of 46,623, almost a 2.5 percent increase.

On Saturday the stock exchange index improved by 2 percent while Iran's national currency, the rial, strengthened by 9 percent against the U.S. dollar.

Foreign currency shops Sunday traded each U.S. dollar for 34,600 rials compared to 36,300 rials Thursday, the eve of the election.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/3d281c11a96b4ad082fe88aa0db04305/Article_2013-06-16-Iran/id-bd7cbf34e0ef4f7f9e4fa39d0c13cf62

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